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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Toxicology. 2020 Jan 18;431:152379. doi: 10.1016/j.tox.2020.152379

Figure 2.

Figure 2.

Effects of Lithium Chloride (LiCl) on DFP-related impairments in axonal transport in rat primary cortical neurons. (A) LiCl attenuates DFP-induced anterograde axonal transport deficits across a range of concentrations (10μM-1mM). (B) 100μM LiCl attenuates DFP-induced deficits in retrograde axonal transport. Histograms depict the mean ±SEM of all MBOs measured per treatment: anterograde transport, n= 55–284 MBOS and a total of 1289 MBOs analyzed; retrograde n=20–140 MBOs and a total of 751 MBOs analyzed. The MBOs analyzed were obtained from 14–21 individual neurons from 3–5 independent experiments. #= p<0.05 compared to DFP *=p<0.05 compared to Vehicle.