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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Toxicology. 2020 Jan 18;431:152379. doi: 10.1016/j.tox.2020.152379

Figure 3.

Figure 3.

Effects of methylene chloride (MB) on DFP-related impairments in axonal transport in rat primary cortical neurons. (A) MB attenuates DFP-induced anterograde axonal transport deficits across a range of concentrations (1nM-100nM). (B) 10nM MB attenuates DFP-induced deficits in retrograde axonal transport. Histograms depict the mean ±SEM of all MBOs measured per treatment: anterograde transport, n= 126–225 MBOs and a total of 1278 MBOs analyzed; retrograde n=78–137 MBOs and a total of 665 MBOs analyzed. The MBOs analyzed were obtained from 14–17 individual neurons from 3–5 independent experiments. #= p<0.05 compared to DFP *=p<0.05 compared to Vehicle.