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. 2010 Sep 8;2010(9):CD002960. doi: 10.1002/14651858.CD002960.pub2

India 1988.

Methods Please see bias table below.
Participants 199 women with eclampsia.
Interventions MgSO4: modified Pritchard's regimen. After the loading dose administered, the IM maintenance dose was administered every 6 hours instead of 4.
Lytic cocktail: Menon's regimen. No further information given.
Outcomes Women: maternal mortality, maternal morbidity, coma > 72 hours, oliguria, anuria, acute renal failure, DIC, respiratory infection, abruptio placentae, atonic PPH, vulval hematoma, postpartum psychosis, cardiac arrest, shock, UTI, bed sore, thrombophlebitis.
Babies: stillbirth, neonatal death, Apgar score < 7, < 4, RDS, meconium aspiration syndrome, septicaemia, hyperbilirubinemia, intracranial haemorrhage, bronchopnuemonia, diarrhoea.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Described as "randomly allocated to two treatment regimens." No further information given.
Allocation concealment? Unclear risk No information given.
Blinding? 
 All outcomes High risk Blinding of the 2 treatment regimens was not possible. Outcome assessment was by the attending clinician, but outcomes used were largely objective, reducing potential for bias.
Incomplete outcome data addressed? 
 All outcomes Unclear risk Data are presented as percentages only.
HHS Vulnerability Disclosure