Skip to main content
. 2013 Oct 3;2013(10):CD002843. doi: 10.1002/14651858.CD002843.pub2

Ellison undated.

Methods Setting: Alexandra Health Centre and University Clinic, a community health clinic and principle provider of health care to the township of Alexandra, South Africa
Enrolment: participants enrolled from 23 June to 12 September 1997
Follow‐up: no follow‐up of index patient scheduled
Participants 1719 index patients, 811 men and 908 females, with any STI syndromically diagnosed were enrolled
Inclusion criteria
  • Any outpatient aged 19‐60 years

  • Diagnosed with STI

  • Not accompanied by partner

  • Not enrolled in the study previously


Exclusion criteria
  • Not specified

Interventions Simple patient referral (n = 433)
Index patient received a standard clinical consultation given by a nurse and received a contact card to be given to partner
Patient referral and health education message (n = 431)
Index patient received a standard clinical consultation, contact card and standardised verbal health education message given by nurse
Patient referral and counselling (n = 430)
Index patient received a standard clinical consultation, contact card and patient‐centred counselling in a private room, conducted by trained lay‐counsellors of same gender
Patient referral with health education message and counselling (n = 425)
Index patient received a standard clinical consultation, contact card and both interventions (health education by the nurse and counselling by lay‐counsellors)
Outcomes
  • Partners presented for care with a notification slip at the health centre (clinical records)

  • The time taken for notified partner to seek treatment at the health centre (clinical records)

  • Contact cards issued and returned (recorded by nurse or lay‐counsellor)

Notes Ethical approval from Committee for Research on Human Subjects of the University of the Witwatersrand in Johannesburg
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Each consecutive patient received an anonymous consecutive number ‐ no specific details on how these numbers were delivered
Allocation concealment (selection bias) High risk Research nurse allocated alternate patients to 1 of 4 groups. Research nurse allocated alternate interventions to each consecutive patient according to a printed schedule (drawn up by project co‐ordinator). Authors acknowledge that research nurse could unwittingly or deliberately influence which patient received each intervention
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Low risk for main outcome, partner treated
Selective reporting (reporting bias) Low risk Outcomes reported in methods section were reported in results section
Other bias Low risk No other risk of bias identified
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Personnel and participant not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk The research personnel at the pharmacy and casualty unit who collected the PN slips were masked to which intervention the participant received
Masked bivariate analysis, unmasked multivariate statistical analysis took place