Kerani 2011.
Methods |
Setting: Public Health‐Seattle & King County (PHSKC), Washington State, US Enrolment: men who had sex with men who were given a diagnosis of gonorrhoea or chlamydia or both were enrolled at the time they were contacted to provide them with partner services between 1 July 2007 and 31 March 2009 Follow‐up: index patients completed a follow‐up interview approximately 2 weeks after enrolment |
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Participants | 75 men with gonorrhoea or chlamydia or both were randomised Inclusion criteria
Exclusion criteria
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Interventions |
Simple patient referral (n = 18) Index patients notify partners themselves Enhanced patient referral (n = 17) Index patient used inSPOT (inspot.org), an Internet‐based PN service. Index patients received a printed card with the site's Internet address or telephonic instructions if not present in STI clinic EPT (n = 16) Index patient received prepackaged medicine to give to 3 different partners. The package also included information on STI, importance of HIV testing, allergy warning to medication, condoms and a free visit to STI clinic. If not present in STI clinic, index patient was telephoned and informed to pick up similar packages at several local pharmacies Combination of EPT and enhanced patient referral (n = 24) Index patient received EPT and inSPOT |
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Outcomes |
Primary outcome
Secondary outcome
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Notes | Ethical approval was received from University of Washington Institutional Review Board. Authors were contacted to clarify type of allocation concealment and whether protocol was available. Exact numbers of partners treated and notified per intervention arm were also requested and the type of adverse events. Authors failed to provide any of the above | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | A computer was used to randomly assign participants ‐ no details given how this was performed |
Allocation concealment (selection bias) | Unclear risk | Not stated |
Incomplete outcome data (attrition bias) All outcomes | High risk | Only 53/75 (70.6%) participants completed the study. Only participants completing the study were included in the analysis |
Selective reporting (reporting bias) | Low risk | Primary outcomes reported in methods section were reported in results section. The protocol was not available from 3 trial registries |
Other bias | Unclear risk | Baseline imbalances (race, type of STI) evident but insufficient to assess whether an important risk of bias existed. Early stopping due to low recruitment rate are not more likely to show extreme results and not considered to be prone to bias |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel not blinded |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Participants and personnel not blinded, outcomes subjective |