Andersen 1998.
Methods |
Setting: general practices in Aarhus, Denmark Enrolment: women who tested positive for Chlamydia trachomatis were randomised ‐ no specific date given Follow‐up: no follow‐up was recorded |
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Participants | 96 women with C. trachomatis were randomised Inclusion criteria
Exclusion criteria
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Interventions |
Patient referral with home sampling (n = 45) Index patients were given a questionnaire about numbers of sexual partners. Index patients were given an envelope with a urine sample home test kit for each partner. The sample was to be sent by the partner to the study laboratory in the provided prepaid envelope Patient referral with office sampling (n = 51) Not stated if index patients completed questionnaire. Index patients were given an envelope containing a contact slip and a request to partner to visit his doctor to request sampling by urethral swab. The doctor was to send a sample in a prepaid envelope to the study laboratory |
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Outcomes |
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Notes | It is not known how many of the partners who tested positive were treated Ethical approval was obtained but no details given Unclear whether consent was obtained |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Used date of birth "Ninety six women with C trachomatis infection seen in general practices in Aarhus County, Denmark, were randomly divided according to their date of birth into an intervention group (45 patients) and a control group (51 patients)" |
Allocation concealment (selection bias) | Unclear risk | Envelopes used for both groups but not stated if they appeared identical. Envelopes for the intervention group contained a 10 mL container that may be palpable |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Test outcome for each partner of every index patient who was randomised was available |
Selective reporting (reporting bias) | Low risk | Outcomes reported in methods section were reported in results section. Trial registries were not searched |
Other bias | Unclear risk | No comparison of baseline characteristics between study arms |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Samples were sent to the laboratory in provided envelopes. It is not stated whether the laboratory personnel knew which procedure was allocated to which group. For urine sample a PCR was performed, for urethral swab enzyme immune assay and if inconclusive a PCR to confirm |