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. 2011 Jun 15;2011(6):CD002851. doi: 10.1002/14651858.CD002851.pub4

Brand 1968.

Methods Randomised, parallel‐arm, controlled trial comparing psycho‐physiological effects of scopolamine, cyclizine and placebo in the prevention of motion sickness
Participants 120 sailors. No information was provided on age or gender.
Interventions Oral doses of placebo, scopolamine (0.1 mg, 0.42 mg, 0.7 mg) or cyclizine (15 mg or 100 mg) administered prior to various tests
Outcomes Objective measurements of salivation, pulse rate, power of accomodation and mental performance
Notes Schulz rating: randomisation B; allocation concealment B; selection bias B; blinding A
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear