Methods |
Randomised, parallel‐arm, controlled trial comparing psycho‐physiological effects of scopolamine, cyclizine and placebo in the prevention of motion sickness |
Participants |
120 sailors. No information was provided on age or gender. |
Interventions |
Oral doses of placebo, scopolamine (0.1 mg, 0.42 mg, 0.7 mg) or cyclizine (15 mg or 100 mg) administered prior to various tests |
Outcomes |
Objective measurements of salivation, pulse rate, power of accomodation and mental performance |
Notes |
Schulz rating: randomisation B; allocation concealment B; selection bias B; blinding A |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |