Gulberg 1999.

Methods	Date of collection: no information provided. Exclusion from analysis: no information provided. Follow‐up period: 7 days.
Participants	Germany Cirrhotic patients with upper gastrointestinal haemorrhage, without infection, or treatment with antibiotics in the previous week, who underwent TIPS. Etiology of bleeding: no information provided. Initial infection assessment: fever, white blood cells, C‐reactive protein. Child‐Pugh class A/B/C: 29/39/14.
Interventions	Experimental: intravenous ceftriaxone, 1g, single dose before TIPS. Control: intravenous ceftriaxone, 2g, single dose before TIPS.
Outcomes	Bacterial infection after TIPS procedure.
Notes	Authors were contacted for the first version of this review.
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	No information provided.
Allocation concealment?	Unclear risk	No information provided.
Blinding? All outcomes	High risk	Not a blinded trial.
Incomplete outcome data addressed? All outcomes	Low risk	No missing outcome data.
Free of selective reporting?	Low risk	The report include all the expected outcomes.
Free of other bias?	High risk	The report support the intervention effects on surrogates of infection.
Intention to treat analysis?	Unclear risk	No information provided.
Sample calculation?	High risk	No sample calculation procedure.