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. 2010 Jan 20;2010(1):CD003051. doi: 10.1002/14651858.CD003051.pub3

Wong 1997.

Methods Randomized controlled clinical trial
Participants Sixty‐six patients undergoing lobectomy segmentectomy or decortication, and presented moderate to severe alveolar air leaks after treating it with measures such as suturing or electrocautering. Thirty‐three (22 male and 11 female of 62 years of median age) were assigned to the control group. Thirty‐three (24 male and 9 female of 55.3 years of median age) were assigned to the fibrin glue group
Interventions A) Intervention group: standard procedures to control air leaks; fibrin glue was applied to leaking areas while ventilation was suspended for a maximum of 2 minutes. B) Control group: Standard procedures to control air leaks with no additional fibrin glue
Outcomes Days of postoperative air leaks, days of intercostal drainage, and of in‐hospital stay
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Quote: "Patients were randomized by a close envelope"
Allocation concealment? Low risk A closed envelope was opened after lung resection
Blinding? 
 All outcomes Unclear risk There is not sufficient information about the blinding of participants and outcome assessors
Incomplete outcome data addressed? 
 All outcomes Low risk Criteria of exclusion and outcomes were reported