| Methods |
A prospective randomized blinded study |
| Participants |
One hundred and thirteen patients undergoing planned open anatomic resection or wedge resection. Thirteen were withdrawn intraoperatively. The remaining 100 patients were randomized. Fifty patients were assigned to treatment group and 50 to control group |
| Interventions |
A) Intervention group: At the end of the procedure patients were treated with an application of fibrin glue. B) Control Group: received no additional treatments |
| Outcomes |
The incidence and duration of air leaks, prolonged alveolar air leaks, the volume of pleural drainage, the time to tube removal and the postoperative length of stay and any complications related to treatment |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
Quote: "Patients were randomly assigned in the operating room to control or treatment groups in a 1:1 ratio by opening a sealed envelop" |
| Allocation concealment? |
Low risk |
Randomization was done by opening a sealed envelop |
| Blinding?
All outcomes |
Low risk |
The presence or absence of air leak and the volume of chest tube drainage were assessed by a blinded observer |
| Incomplete outcome data addressed?
All outcomes |
Low risk |
Excluded patients and outcomes were well reported |
