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. 2010 Jan 20;2010(1):CD003051. doi: 10.1002/14651858.CD003051.pub3

Fleisher 1990.

Methods Randomized controlled clinical trial
Participants Twenty‐eight patients undergoing uncomplicated lobectomy. Fourteen (9 male and 5 female with a mean age of 63.8 years) were included in the fibrin group. Fourteen (8 male and 6 female of 59.0 years of mean age) were controls
Interventions A) Intervention group: Division of lung fissures with stapling devices; two millilitres of fibrin glue were applied to staple lines and any cut surfaces of the lung regardless of the presence or absence of air leaks. B) Control group: Division of lung fissures with stapling devices, without additional fibrin glue
Outcomes Duration of postoperative air leaks, chest tube drainage and postoperative hospitalization
Notes Patients were randomized by their hospital record number
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? High risk Sequence was generated by their hospital record number
Allocation concealment? High risk Assignement of either group was made before thoracotomy by the surgeon according the hospital record number
Blinding? 
 All outcomes Unclear risk No information reported about this domain
Incomplete outcome data addressed? 
 All outcomes Low risk No missing outcome data in the study