Figure 10.
Effects of DEHP and DiNP on FSH and inhibin B at 6 months post-dosing. Adult female CD-1 mice were orally dosed for 10 days with either vehicle control (corn oil), DEHP (20 μg/kg/day – 200 mg/kg/day), or DiNP (20 μg/kg/day – 200 mg/kg/day). Mice were euthanized in the diestrous stage of the estrous cycle 6 months post-dosing and sera were collected for analysis of FSH (n = 4–11 mice/group) (A) and inhibin B (n = 3–11 mice/group) (B). Data are represented as means ± standard error. Statistically significant difference when compared to control (p ≤ 0.05) is denoted with an asterisk (*).