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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2020 Mar 10;393:114952. doi: 10.1016/j.taap.2020.114952

Figure 9.

Figure 9.

Effects of DEHP and DiNP on sex steroid hormones at 6 months post-dosing. Adult female CD-1 mice were orally dosed for 10 days with either vehicle control (corn oil), DEHP (20 μg/kg/day – 200 mg/kg/day), or DiNP (20 μg/kg/day – 200 mg/kg/day). Mice were euthanized in the diestrous stage of the estrous cycle 6 months post-dosing and sera were collected for analysis of testosterone (n = 5–11 mice/group) (A), progesterone (n = 5–11 mice/group) (B), and estradiol (n = 5–11 mice/group) (C). Data are represented as means ± standard error. Statistically significant difference when compared to control (p ≤ 0.05) is denoted with an asterisk (*). Borderline statistical significance (0.05 < p ≤ 0.10) is denoted with a caret (^).