Figure 4. Identification process of somatic variants in FENDRR and FOXF1.

(A) Schematic of bioinformatics SNV detection workflow. (B) Extraction of functionally relevant somatic mutations for FOXF1 and FENDRR in lung cancer. Variants were filtered for annotation in dbSNP, 1000genomes, ExAC, NCI60, somatic and functionally impairment. From dbSNP or the 1000 genomes variants with frequencies above 1% were excluded.