Kongsakon 2005.

Methods	Randomised, double‐blind, 14‐day study. Recruited from a probation center.
Participants	20 males who met DSM‐IV criteria for amphetamine dependence; mean age = 24.3 years
Interventions	(1) mirtazapine 15‐60 mg/day with an initial dose of 15 mg (n = 9) (2) placebo (n = 11); dose titrations during the study was based on subjects clinical response to medication
Outcomes	Discontinuation rate, AWQ score, MADRS score
Notes	Used a last observation carried forward method for intent‐to‐treat analysis. Country of origin: Thailand
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	"Twenty cases . . .were enrolled and randomized."
Allocation concealment?	Unclear risk	"Twenty cases . . .were enrolled and randomized." Method of allocation concealment not specified.
Incomplete outcome data addressed? All outcomes	Low risk	Outcome analysis was conducted using a last observation carried forward method of intent‐to‐treat analysis.
Free of selective reporting?	Low risk
Blinding (subjective outcomes)? All outcomes	Unclear risk	Blindness of participants, personnel, and assessors were not specified.
Blinding (objective outcomes)? All outcomes	Low risk	Blindness of participants, personnel, and assessors were not specified.