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. 2010 Oct 6;2010(10):CD002292. doi: 10.1002/14651858.CD002292.pub3

Morel 1984.

Methods Randomised but not blind
Disease control = number new blisters between days 21 to 51
Follow‐up: 51 days ( = treatment period)
Participants 50 participants with BP confirmed by IF studies.
Interventions A: 24/26 prednisolone 0.75 mg/kg/day.
B: 22/24 prednisolone 1.25 mg/kg/day.
Outcomes
  1. New blister formation: at day 21 and 51

Notes 2 dropouts in each group, no reasons given, and not included in analysis
Erythromycin used for infection but its anti‐inflammatory effect not evaluated or commented upon
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "using a single table of pre‐established and balanced randomisation for all 8 patients." (Translation, page 926).
Allocation concealment (selection bias) Unclear risk No details given.
Blinding (performance bias and detection bias) 
 All outcomes High risk No. No details given.
Incomplete outcome data (attrition bias) 
 All outcomes High risk 2 dropouts in each group, no reasons given, and not included in analysis.
Selective reporting (reporting bias) Low risk New blister formation at days 21 and 51 reported.
Other bias Unclear risk Some participants that could have been recruited were excluded on the grounds that they were able to take part in a parallel study involving plasma exchanges.