NCT00802243.

Trial name or title	Leflunomide associated with topical corticosteroids for bullous pemphigoid. An open prospective study
Methods	Open label, uncontrolled, single group assignment, efficacy study
Participants	54 participants with bullous pemphigoid
Interventions	40 g topical clobetasol propionate cream per day plus 20 mg leflunomide per day
Outcomes	Primary outcomes: Stage 1: complete clinical remission after 6 months treatment for 9 participants at least among 15 appraisable participants Stage 2: complete clinical remission after 6 months treatment for 27 participants at least among 43 appraisable participants Secondary outcomes: To determine the rate of clinical complete remission at M9 and M12 To estimate the number of participants with immunological remission at M6, M9, and M12 To evaluate monthly the tolerance of leflunomide
Starting date	September 2007
Contact information	Christophe Bedane (christophe.bedane@chu‐limoges.fr) Limoges University Hospital Limoges 87042  France
Notes	Christophe