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. 2020 Feb 20;45(5):1373–1384. doi: 10.3892/ijmm.2020.4509

Figure 4.

Figure 4

AZD8797 reduces neuronal apoptosis after rat SCI. (A) The representative examples of the western blot analysis results for the expression of CX3CL1, CX3CR1, caspase 3, Bcl-2 and Bax in four groups as indicated 10 days after SCI. (B) Quantitative analysis of (B) CX3CL1, (C) CX3CR1, (D) Bcl2, (E) caspase 3 and (F) Bax expression in the western blotting in the sham, Model, Inhibitor and Me groups 10 days after SCI. Data is presented as means ± standard deviation. ***P<0.001 vs. sham, nsP>0.05 vs. Injury, &P<0.05 and &&P<0.01 vs. Me. #P<0.05, ##P<0.01 and ###P<0.001 vs. Injury. n=10. Me, methylprednisolone; ns, not significant; GFAP, glial fibrillary acidic protein; SCI, spinal cord injury; CX3CL1, C-X3-C motif chemokine ligand 1CX3CR1, C-X3-C motif chemokine receptor 1.