Figure 4.

Effect of curculigoside on MPTP opening. (A) MPTP opening was induced by CaCl₂. (B) Statistical analysis for MPTP opening. Minimum optical density (min OD) represents the OD value recorded at the end of the experiment (10 min); maximum optical density (max OD) represents the OD value recorded at the onset of the experiment (0 min). Min/max OD is negatively associated with the extent of MPTP opening. ^**P<0.05 vs. the control group, ^*P<0.05 vs. the H/R group, ^#P<0.05 vs. the curculigoside-treated group. MPTP, mitochondrial permeability transition pore; H/R, hypoxia/reoxygenation; Cur, curculigoside; ATR, atractyloside.