Skip to main content
. 2014 Jun 19;2014(6):CD003101. doi: 10.1002/14651858.CD003101.pub3

Newman 1997.

Methods 'Prospectively randomised.'
Participants 58 women requiring induction for post dates pregnancy, or gestational diabetes.
Inclusion criteria: unfavourable cervix (BS < 7).
Interventions 2 mg PGE2 vaginally (n = 28) followed by repeat doses at 24 and 48 hours.
Control group managed expectantly (n = 30) until 44 weeks or if non‐reassuring NST or favourable cervix (BS > 7).
Outcomes Rate of spontaneous labour, delivery intervals, mode of delivery, hyperstimulation, neonatal outcomes.
Notes Limited data available as extracted from abstract.
Medical University of South Carolina, USA.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Prospectively randomised but method of random sequence generation not reported.
Allocation concealment (selection bias) Unclear risk Prospectively randomised but method of concealment of allocation not reported.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No blinding.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No blinding.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No randomised patients lost to follow‐up.
Selective reporting (reporting bias) Unclear risk Unclear which outcomes prespecified.
Other bias Unclear risk Small, single centre RCT, abstract only.