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The cytotoxic and antiviral activity of compounds 2, 5 and 7.
| Compound | CC50 | IC50 (μM ± SD)a A/Yucatán/2370/09 | IC50 (μM ± SD)a A/México/InDRE797/10 |
|---|---|---|---|
| 2 | >100 | 62.31 ± 3.05 | NA |
| 5 | >100 | 30.77 ± 2.10 | 62.28 ± 2.65 |
| 7 | >100 | 13.70 ± 3.80 | 19.47 ± 0.93 |
| OC | >100 | 0.025 ± 0.05 | R |
CC50: Half maximal cytotoxic concentration.
IC50: Inhibitory concentration.
NA: No activity.
OC: Oseltamivir carboxylate as a positive control.
R: resistant virus to OC.
Mean values of three replicates.
