Table 2.

Idiopathic right ventricular outflow tract tachycardia vs arrhythmogenic right ventricular cardiomyopathy-related ventricular tachycardia

	RVOT-VT	ARVC
Disease inheritance	No	Yes (AD)
Genetic defect	No	Desmosomal genes-mutations
Symptoms	Palpitations, pre-syncope	Palpitations, syncope, cardiac arrest
ECG abnormalities	Normal	Right precordial T-wave inversion, ε waves, right precordial QRS prolongation with delayed S-wave upstroke, and terminal activation delay (>55 ms), low QRS voltages
Imaging	Normal	Structural and functional RV abnormalities
Biopsy	Normal	Fibrofatty myocardial replacement
Morphology of VT	NSVT repetitive monomorphic; LBBB usually with inferior QRS axis	LBBB Usually with left deviation
Multiple VT morphologies	No	Yes
VT mechanism	Enhanced automaticity and triggered activity	Scar-related re-entry
Typical site of VT origin	Anteroseptal RVOT	Non-septal RVOT
RV EVM	Normal	Low-voltage areas
Programmed ventricular stimulation	Non-inducible VT	Inducible VT

AD, autosomal dominant; EVM, endocardial voltage mapping; LBBB, left bundle branch block; NSVT, non-sustained ventricular tachycardia; RV, right ventricle; RVOT, right ventricular outflow tract; TWI, T-wave inversion; VF, ventricular fibrillation; VT, ventricular tachycardia.