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. 2020 Mar 23;12(6):5183–5194. doi: 10.18632/aging.102940

Table 2. Univariate and multivariate regression analyses associated with prognosis in CRC patients.

Characteristics Subset Univariate analysis Multivariate analysis
P-value HR (95% CI) P-value HR (95% CI)
Ages (years) < 60/≥ 60 0.437 0.817 (0.387–1.608) - -
Gender Male/female 0.905 0.921 (0.494–1.864) - -
Tumor size < 5 cm/ ≥ 5 cm 0.372 1.295 (0.702–2.853) - -
Location Colon/rectum 0.974 2.130 (0.534–2.105) - -
Depth of tumor T1 + T2/T3 + T4 0.028 8.627 (1.148–60.113) 0.237 4.083 (0.549–30.370)
Differentiation Well + moderately/poorly 0.013 1.468 (1.203–5.461) 0.083 2.031 (0.871–5.617)
Tumor stage I + II/III + IV 0.000 9.855 (4.021–28.654) 0.001 8.046 (1.468–23.656)
Distant metastasis Present/absent 0.426 0.713 (0.191–1.750) - -
AGAP2-AS1 High/low 0.001 3.774 (1.652–8.382) 0.023 2.405 (1.137–6.023)