Table 1. Significantly enriched gene sets by DEGs between verbenalin-treated and control cells.
| Gene set* | Systematic name, Gene Ontology | No. of genes in set | No. of Genes in Overlap | p-value | FDR q-value |
| Genes up-regulated in brain from patients with Alzheimer’s disease | M12921 | 1691 | 44 | 1.31 e-12 | 2.87 e-9 |
| Neurogenesis1 | M13908, GO:0022008 | 1402 | 36 | 2.42 e-10 | 1.87 e-7 |
| Regulation of neuron differentiation2 | M12739, GO:0045664 | 554 | 19 | 6.44 e-8 | 1.25 e-5 |
| Regulation of nervous system development3 | M11450, GO:0051960 | 750 | 22 | 9.09 e-8 | 1.65 e-5 |
| Genes down-regulated in brain from patients with Alzheimer’s disease | M17728 | 1237 | 29 | 1.02 e-7 | 2.99 e-5 |
| Table 1. Significantly enriched gene sets by DEGs between verbenalin-treated and control cellsGenes up-regulated during later stage of differentiation of Oli-Neu cells (oligodendroglial precursor) | M2368, | 570 | 9 | 1.64 e-5 | 1.17 e-2 |
| Neuromuscular process4 | M15744, GO:0050905 | 97 | 4 | 1.15 e-4 | 2.84 e-2 |
*GSEA online software (http://software.broadinstitute.org/gsea/index.jsp).
1Generation of cells within the nervous system.
2Any process that modulates the frequency, rate or extent of neuron differentiation.
3Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
4Any process pertaining to the functions of the nervous and muscular systems of an organism.