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. 2020 Apr 3;13:2833–2842. doi: 10.2147/OTT.S238958

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© 2020 Li et al.

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PHI reduced cell viability in pancreatic cancer cells. (A) Chemical structure of PHI. (B) Effect of PHI on the viability of two human PC cell lines (PANC-1, SW1990) and normal pancreatic cell line (HPNE). Cells were treated with increasing concentrations of PHI for 24 h and cell viability was measured by MTT assay. (C, D) Effect of varying PHI concentrations on the colony-forming ability of PANC-1, SW1990, and HPNE cells. Cells were incubated with PHI for 12 h and allowed to grow for 10 days. Colonies were stained by crystal violet dye. *p<0.05, **p<0.01, vs DMSO group.