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. 2020 Apr 3;13:2873–2886. doi: 10.2147/OTT.S243533

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© 2020 Li et al.

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Down-regulation of hsa_circ_0087862 inhibited tumor growth in vivo. (A and F) Xenograft tumor volume was measured every 7 days after injection. (B and G) Xenograft tumor weight was detected on the 28th day after injection. (C and H) Xenograft tumor tissues of each group were shown. (D and I) Xenograft tumor was subjected to immunohistochemistry and Tunel staining to detected expression of RAB3D, Ki67 and apoptosis. (E and J) Expression of hsa_circ_0087862, miR-1253 and RAB3D in Xenograft tumor was detected by qRT-PCR. **P < 0.01. ***P < 0.001.