Table 5.
Associations Between 896A>G Genotype and Clinicopathological Variables
| Total Population | AA (n) | AG (n) | P |
|---|---|---|---|
| BMI | 24 (22–26) (169) | 24 (22–29) (31) | 0.42 |
| FBS (mg/dL) | 109 (96 −184) (169) | 144 (105 −246) (31) | 0.04 |
| HDL (mg/dL) | 45 (37–56) (169) | 42 (39–46) (31) | 0.31 |
| LDL (mg/dL) | 89 (78–05) (169) | 98 (76 −109) (31) | 0.99 |
| TG (mg/dL) | 136.8 ± 73.5 (169) | 159 ± 64.1 (31) | 0.45 |
| Chol (mg/dL) | 180.4 ± 37.3 (169) | 179.8 ± 39.1 (31) | 0.98 |
| In cases only | |||
| HbA1C (%) | 4.1 ± 0.3 (81) | 5.8 ± 0.8 (19) | 0.06 |
| OGTT (mg/dl) | 109.8 ±132.5 (81) | 163.5 ± 155 (19) | 0.04 |
| T2DM duration (y) | 9.7 ± 5.3 (76) | 8.6 ± 5.4 (15) | 0.45 |
| Hypertension (n) | 31 | 6 | 0.58 |
| Family history IHD (n) | 28 | 9 | 0.29 |
| Statin therapy (n) | 41 | 8 | 0.63 |
| Nephropathy (n) | 10 | 1 | 0.37 |
Notes: Parametric values are presented as mean ± standard deviation and non-parametric data are presented as median (Q1-Q3). Data were evaluated using χ2-test for Hypertension, IHD, Statin therapy and Nephropathy; Mann–Whitney U-test for Age, BMI, HDL, LDL, TG and FBS; t-test for the other variables. P < 0.05 was considered as statistically significant.
Abbreviations: OGTT, oral glucose tolerance test; IHD, ischemic heart disease.