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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Epidemiology. 2020 May;31(3):432–440. doi: 10.1097/EDE.0000000000001132

Figure. Figure illustrating the study design for the main analyses of ADT and secondary analysis of current use of ADT.

Figure.

A. Main analysis: Allocation to treatment groups in 3 hypothetical patients.

B. Analysis of ADT dose response.

C. Analysis of current use of ADT (start/stop time-varying exposure) analysis.

ADT, androgen deprivation therapy.

aDuration of user time depends on the number of DDD in the prescription plus a residual period as described.

bAssuming on receipt of 3rd dispensed ADT usage exceeds 365 DDDs.