Table 2:

Self-reported Hearing loss (2012) and risk of incident subjective cognitive function decline^* in the Nurses’ Health Study

	SCF Score ≥ 1				SCF Score ≥ 2
Hearing Status		Cases	Age-adjusted OR (95% CI)	Multivariable-adjusted OR† (95% CI)		Cases	Age-adjusted OR (95% CI)	Multivariable-adjusted OR† (95% CI)
No hearing loss		2188	1.00 (ref)	1.00 (ref)		738	1.00 (ref)	1.00 (ref)
Mild hearing loss		1180	1.40 (1.30, 1.52)	1.35 (1.25, 1.47)		305	1.47 (1.29, 1.68)	1.39 (1.22, 1.59)
Moderate hearing loss		510	1.47 (1.31, 1.64)	1.39 (1.24, 1.56)		59	1.61 (1.35, 1.92)	1.48 (1.24, 1.78)
Severe hearing loss		113	1.53 (1.23, 1.90)	1.40 (1.21, 1.75)		13	1.40 (0.98, 1.99)	1.23 (0.86, 1.76)
p-trend			<0.001	<0.001			<0.001	<0.001

^*Incident subjective cognitive function decline defined as Subjective Cognitive Function Score (SCF) ≥ 1 or ≥ 2 at follow-up

^†Adjusted for: Age, race, education, socioeconomic status (spouse’s education), BMI, waist circumference, physical activity, smoking, hypertension, diabetes, hypercholesterolemia, depression, Mental Health Index (MHI-5), tinnitus, aspirin use, non-steroidal anti-inflammatory drug (NSAID) use, acetaminophen use, and AMED adherence score.

Abbreviations:

OR: odds ratio

BMI: body mass index

AMED: Alternate Mediterranean diet