Table 2:
Baseline Areal Bone Mineral Density and Changes over 12 Months in the Surgical and Non-Surgical Groups
| Baseline Measures (Mean ± SEM) |
Change over 12-months [Mean (95% CI)] |
P-value comparing changes over 12 months in surgical vs. non-surgical groups |
||||
|---|---|---|---|---|---|---|
| Non-Surgical (n=21) |
Surgical (n=22) |
Non-Surgical (n=21) |
Surgical (n=22) |
Adjusted for age, sex, race and baseline |
Adjusted for age, sex, race, baseline and change in BMI |
|
| 1/3 Radius BMD (g/cm2) | 0.695 ± 0.012 | 0.727 ± 0.013 | 0.021 (−0.007, 0.048) | 0.001 (−0.028, 0.030) | 0.969 | 0.434 |
| 1/3 Radius BMD Z-score | 0.532 ± 0.319 | 0.305 ± 0.267 | −0.224 (−0.471, 0.024) | 0.047 (−0.174, 0.269) | 0.057 | 0.990 |
| Femoral Neck BMD (g/cm2) | 1.082 ± 0.025 | 1.088 ± 0.024 | 0.007 (−0.020, 0.034) | −0.080 (−0.123, −0.037 | 0.0007 | 0.067 |
| Femoral Neck BMD Z-score | 1.755 ± 0.240 | 1.881 ± 0.263 | −0.110 (−0.341, 0.122) | −0.947 (−1.310, −0.584) | 0.0006 | 0.097 |
| Total Hip BMD (g/cm2) | 1.182 ± 0.023 | 1.183 ± 0.031 | 0.001 (−0.021, 0.023) | −0.086 (−0.125, −0.047) | 0.0002 | 0.240 |
| Total Hip BMD Z-score | 1.864 ± 0.220 | 1.776 ± 0.314 | −0.162 (−0.294, −0.030) | −0.858 (−1.155, −0.561) | <0.0001 | 0.161 |
| Lumbar Spine BMD (g/cm2) | 1.098 ± 0.022 | 1.143 ± 0.021 | 0.018 (−0.007, 0.042) | −0.021 (−0.045, 0.002) | 0.244 | 0.185 |
| Lumbar Spine BMD Z-score | 1.064 ± 0.241 | 1.218 ± 0.177 | −0.071 (−0.244, 0.101) | −0.416 (−0.681, −0.150) | 0.147 | 0.315 |
| Whole Body BMD (g/cm2) | 1.095 ± 0.016 | 1.095 ± 0.016 | 0.025 (−0.001, 0.051) | 0.012 (−0.012, 0.035) | 0.723 | 0.030 |
| Whole Body BMD Z-score | 0.282 ± 0.242 | 0.032 ± 0.241 | 0.005 (−0.304, 0.313 | −0.091 (−0.398, 0.217) | 0.613 | 0.030 |
| WBLH BMD (g/cm2) | 0.996 ± 0.014 | 1.000 ± 0.016 | 0.016 (−0.008, 0.040) | −0.006 (−0.033, 0.022 | 0.505 | 0.034 |
BMD: Bone mineral density; WBLH: whole body less head; Significant changes from baseline and significant p values are bolded.
Baseline measures were compared using the Student t-test; Within group changes over 12 months were assessed using the paired t-test
Differences between surgical and non-surgical groups were assessed using multivariable analyses after adjusting for baseline measures, age, sex, race +/− change in BMI over 12 months