Table 4:

Associations of Changes in Anthropometric Measures and Body Composition with Changes in Bone Parameters Over 12 Months

	Δ BMI z-score		Δ Lean Mass		Δ Fat Mass		Δ 25(OH)D		Δ Physical activity
	ρ	p	ρ	p	ρ	p	ρ	p	ρ	p
DXA measures
Δ FN BMD Z-score	0.487	0.001	0.533	0.0004	0.404	0.010	−0.018	0.916	−0.90	0.602
Δ Total Hip BMD Z-score	0.615	<0.0001	0.715	<0.0001	0.544	0.0003	−0.135	0.420	0.295	0.081
Δ Lumbar Spine BMD Z-score	0.177	0.267	0.212	0.184	0.072	0.654	0.122	0.459	−0.209	0.215
Distal Tibia
Δ Cortical Area (mm2)	0.396	0.031	0.487	0.006	0.357	0.053	−0.039	0.840	0.229	0.262
Δ Trabecular Area (mm2)	−0.472	0.008	−0.563	0.001	−0.409	0.025	−0.004	0.983	−0.198	0.332
Δ Cortical Thickness (mm)	0.370	0.044	0.454	0.011	0.349	0.076	0.086	0.659	0.144	0.483
Δ Cortical Porosity (%)	0.341	0.065	0.164	0.386	0.143	0.452	−0.475	0.009	0.119	0.563
Δ Trabecular Number (1/mm)	0.527	0.003	0.400	0.028	0.460	0.009	−0.317	0.094	0.319	0.112
Δ Trabecular Separation (mm)	−0.513	0.004	−0.426	0.013	−0.374	0.042	0.210	0.275	−0.311	0.122
Δ Cortical vBMD (mgHA/cm3)	−0.194	0.306	−0.193	0.306	−0.253	0.177	0.398	0.033	−0.118	0.566
Δ Stiffness (kN/mm)	−0.081	0.671	−0.007	0.968	−0.232	0.217	0.243	0.205	−0.295	0.144
Distal Radius
Δ Cortical Porosity (%)	0.375	0.041	0.142	0.455	0.248	0.187	−0.396	0.037	0.152	0.440
Δ Cortical vBMD (mgHA/cm3)	−0.244	0.193	−0.081	0.669	−0.153	0.419	0.233	0.232	0.142	0.471
Δ Trabecular vBMD (mgHA/cm3)	0.334	0.071	0.278	0.137	0.379	0.039	−0.332	0.085	0.268	0.168

Δ: Change; FN: femoral neck; vBMD: volumetric bone mineral density; 25(OH)D: 25-hydroxy vitamin D. Significant p values are bolded; Spearman correlations (ρ) and the corresponding p value are reported