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. 2020 Jan 20;37(2):377–390. doi: 10.1007/s10585-019-10016-z

Table 3.

Comparison of postoperative non-ambulatory (n = 40) and ambulatory (n = 61) patients

Characteristic All Non-ambulatory postoperatively Ambulatory postoperatively p-value
Number of patients 101 40 61
Sex (%) < 0.00012
 Male 74 (73%) 27 (67.5%) 47 (77%)
 Female 27 (27%) 13 (32.5%) 14 (23%)
First symptom (%)
 Paresis 64 (63%) 30 (75%) 34 (67%) 0.48952
 Pain 20 (20%) 5 (13%) 15 (24%) 0.20162
 Sensory deficit 12 (12%) 4 (10%) 8 (13%) 0.75922
 Bowl/bladder dysfunction 5 (5%) 1 (2.5%) 4 (7%) 0.70922
Duration of first symptom (median, IQR / mean ± SD) 5, 2–14 days / 17.3 ± 42.5 days 7, 2–14 days / 12.85 ± 18.5 days 5, 2.5–14 days / 20.1 ± 52.6 days 0.32291
KPI on admission
 < 50% 73 (72%) 38 (95%) 35 (57%) < 0.00012
 > 40% 28 (28%) 2 (5%) 26 (43%)
FG on admission (%)
 Grade < D 81 (80%) 40 (100%) 41 (67%) < 0.00012
 Grade > C 20 (20%) 0 (0%) 20 (33%)
Symptoms on admission (%)
 Paresis 101 (100%) 81 (100%) 20 (100%) > 0.99992
 Back pain 49 (49%) 17 (43%) 32 (52%) 0.41642
 Radiating pain 13 (13%) 2 (5%) 11 (18%) 0.07112
 Sensory deficit 83 (82%) 32 (80%) 51 (84%) 0.79112
 Bladder dysfunction 60 (59%) 29 (73%) 31 (51%) 0.03872
 Bowl dysfunction 25 (25%) 19 (48%) 6 (10%) < 0.00012
Duration of paresis (median, IQR / mean ± SD) 4.5, 2–10 days / 11.6 ± 26.3 days 4, 1–14 days / 9.3 ± 15.3 days 5, 2–10 days / 13.1 ± 31.6 days 0.42681
Degree of paresis (%)
 > Grade 3/5 BMRC 24 (24%) 1 (3%) 23 (62%) < 0.00012
 < Grade 4/5 BMRC 77 (76%) 39 (97%) 38 (38%)
Ambulatory status on admission
 Able to walk 20 (20%) 0 (0%) 20 (33%) < 0.00012
 Unable to walk 81 (80%) 40 (100%) 41 (67%)
Duration of inability to walk (median, IQR / mean ± SD) 48, 24–96 h / 71 ± 76.5 h 24, 24–72 h / 70 ± 89.7 h 48, 24–96 h / 72 ± 62.9 h 0.91072
Tokuhashi score (%)
 0–8 63 (62%) 30 (75%) 33 (54%) 0.03822
 9–11 35 (35%) 10 (25%) 25 (41%) 0.13472
 12–15 3 (3%) 0 (0%) 3 (5%) 0.27522
ASA score (%)
 < ASA 3 26 (26%) 5 (14%) 17 (28%) 0.13372
 > ASA 2 75 (74%) 32 (86%) 43 (72%)
Time to surgery (%)
 < 24 h after admission 72 (72%) 30 (75%) 42 (70%) 0.65372
 > 24 h after admission 28 (28%) 10 (25%) 18 (30%)
Duration of surgery (median, IQR / mean ± mean) 130, 105–160 min / 138.4 ± 49.5 min 130, 105–153 min / 139 ± 50 min 131, 100–161 min / 138 ± 49.7 min 0.92771
Complications (%) 6 (6%) 3 (7.5%) 3 (5%) 0.25892
Revision surgery (%) 4 (4%) 1 (3%) 3 (5%) > 0.99992
Hospital length of stay (median, IQR / mean ± SD) 8, 6–12 days / 9 ± 4.7 days 7.5, 4–12 days / 8.5 ± 4.8 days 8, 6–12 days / 9.4 ± 4.7 days 0.36761
Improvement on discharge (%)
 KPI 75 (74%) 24 (60%) 51 (84%) 0.01072
 Frankel Grade 61 (61%) 11 (28%) 50 (82%) < 0.00012
 Ambulation 41 (41%) 0 (0%) 41 (67%) < 0.00012
 Paresis 69 (68%) 23 (58%) 46 (75%) 0.08022
 Back pain 23 (23%) 7 (50%) 16 (50%) > 0.99992
 Radiating pain 7 (7%) 0 (0%) 7 (64%) 0.19232
 Sensory deficit 15 (15%) 3 (10%) 12 (25%) 0.14542
 Bladder dysfunction 19 (19%) 4 (14%) 15 (54%) 0.00412
 Bowl dysfunction 5 (5%) 2 (11%) 3 (60%) 0.04822

SD standard deviation, IQR inter quartile range, FG Frankel Grade, KPI Karnofsky Performance Index, BMRC British Medical Research Council, ESCC Epidural Spinal Cord Compression, SINS Spinal Instability Neoplastic Score, ASA American Society of Anesthesiologists

1Students t-test

2Fishers exact test