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. 2020 Apr 7;10:5996. doi: 10.1038/s41598-020-62876-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Two DC-SIGNR variants identified and SFTS virus infection. (a) DC-SIGNR4r (left) and DC-SIGNR7r (right) were expressed in Jurkat cells by lentivirus vectors and their expressions were analysed by flow cytometry with control IgG (thin line) and anti-DC-SIGNR IgG (bold line). (b) Jurkat cells expressing a control molecule (fCD2ΔCT), DC-SIGNR4r, or DC-SIGNR7r were inoculated with iVLP(Venus) (left) or authentic SFTS virus (right) at the indicated MOIs and the expression of a reporter (Venus) or a viral protein (NP) in the cells was examined by flow cytometry. Data shown are means of duplicate experiments.