Figure 2. Comparison of the humoral adjuvanticities of three TLR ligands delivered via two different ways.

Mice were immunized two times with the same dose of indicated antigen/adjuvant combinations, and their serum samples were assayed for the antigen-specific IgG antibody at the indicated times by ELISA using VP2 as the antigen. * or ** indicates P<0.05 or P<0.01 as compared with the VP2 control or between co-administered (A) and geneticaly fused (B) TLR ligands.