Table 1. Antidiabetic effect of ZnONPs on STZ-induced diabetic mice.
Groups | Blood glucose levels (mmol/l) | |||
---|---|---|---|---|
Dose | Fasting glucose levels | Glucose levels after 2 h | % of inhibition | |
G-I (Control: Distilled water) | 1 ml/mice (oral) | 18.68 ± 0.34 | 18.54 ± 0.16 | - |
G-II (ZnONPs) | 14 mg/kg b.w. (oral) | 18.32 ± 0.22 | 11.04 ± 0.22* | 39.74 |
G-III (ZnONPs + Insulin) | 7 mg/kg b.w. (oral) + 0.2 U/50 g (s.c.) | 18.62 ± 0.27 | 11.40 ± 0.21* | 38.78 |
G-IV (Standard: Insulin) | 0.4 U/50 g (s.c.) | 18.60 ± 0.19 | 9.56 ± 0.32* | 48.60 |
Mean ± S.E.M. (n=5). Data were analyzed using one-way ANOVA followed by Dunnett’s t test and compared with control.
P<0.005 was considered significant.