Table 2. Hypoglycemic activity of ZnONPs.
Groups | Blood glucose levels (mmol/l) | |||
---|---|---|---|---|
Dose | Fasting glucose levels at 0 h | Glucose levels after 2 h | % of inhibition | |
G-I (Control: Distilled water) | 1 ml/ mice (oral) | 4.10 ± 0.12 | 3.98 ± 0.06 | - |
G-II (ZnONPs, mild dose) | 8 mg/kg b.w. (oral) | 3.84 ± 0.19 | 2.98 ± 0.15* | 25.13 |
G-III (ZnONPs, moderate dose) | 14 mg/kg b.w. (oral) | 4.12 ± 0.13 | 2.82 ± 0.12† | 29.15 |
G-IV (Standard: Glibenclamide) | 10 mg/kg b.w. (oral) | 4.04 ± 0.10 | 2.02 ± 0.15† | 49.25 |
Mean ± S.E.M. (n=5). Data were analyzed using one-way ANOVA followed by Dunnett’s t test and compared with control.
P<0.01.
P<0.005 was considered significant.