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. 2020 Apr 7;40(4):BSR20192257. doi: 10.1042/BSR20192257

Figure 3. SOCS5 was the target gene of micro-RNA802.

Figure 3

(A) Targetscan predicted the target binding sites between SOCS5 and miR-802. (B) RT-qPCR was used to detect the expression of SOCS5 in colon mucosa of healthy control (HC) and IBD patients; ***, P < 0.001. (C) Correlation analysis between miR-802 and SOCS5. (D) RT-qPCR was used to detect the expression of SOCS5 in PBMC of HC and IBD patients; ***, P < 0.001. (E) The results of luciferase reporter gene activity detection; *, P < 0.05. (F) The RT-qPCR was used to detect the expression of SOCS5 in CD4+ cells after transfection. *, P < 0.05. One-way ANOVA was used for the present study. Tukey’s multiple comparison test was used for the pairwise comparison after ANOVA.