Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 9;19(5):3227–3238. doi: 10.3892/etm.2020.8590

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Suo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Effect of HO-1 on PM2.5 exposure-induced cell apoptosis in human melanocytes. PIG1 or PIG3V cells were pretreated with 10 µM ZnPP or 10 µM Hemin for 2 h prior to incubation with (200 µg/ml) PM2.5 for 24 h. HO-1 expressions in (A) PIG1 and (B) PIG3V cells. Effects of HO-1 on the reduction of cell viability induced by PM2.5 in (C) PIG1 and (D) PIG3V cells. ^*P<0.05 vs. 0 µg/ml PM2.5, ^#P<0.05 vs. 200 µg/ml PM2.5. Effects of HO-1 on PM2.5 induced cell apoptosis in (E) PIG1 and (F) PIG3V cells. Data are presented as the mean ± SD. n=6. ^*P<0.05 vs. respective Ctrl; ^#P<0.05 vs. PM2.5. PM2.5, particulate matter 2.5; HO-1, heme oxygenase-1; ZnPP, Zinc protoporphyrin; Hemin, hemin chloride; Ctrl, control; PI, propidium iodide.

Effect of HO-1 on PM2.5 exposure-induced cell apoptosis in human melanocytes. PIG1 or PIG3V cells were pretreated with 10 µM ZnPP or 10 µM Hemin for 2 h prior to incubation with (200 µg/ml) PM2.5 for 24 h. HO-1 expressions in (A) PIG1 and (B) PIG3V cells. Effects of HO-1 on the reduction of cell viability induced by PM2.5 in (C) PIG1 and (D) PIG3V cells. ^*P<0.05 vs. 0 µg/ml PM2.5, ^#P<0.05 vs. 200 µg/ml PM2.5. Effects of HO-1 on PM2.5 induced cell apoptosis in (E) PIG1 and (F) PIG3V cells. Data are presented as the mean ± SD. n=6. ^*P<0.05 vs. respective Ctrl; ^#P<0.05 vs. PM2.5. PM2.5, particulate matter 2.5; HO-1, heme oxygenase-1; ZnPP, Zinc protoporphyrin; Hemin, hemin chloride; Ctrl, control; PI, propidium iodide.