Table 4. Progression of CAC severity after TIR.
| Cardiovascular structures | Patient group (N=35) | Control group (N=65) | P | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| None | Mild | Mod | Severe | None | Mild | Mod | Severe | |||
| LM | 28 (80.0) | 5 (14.3) | 0 | 2 (5.7) | 59 (90.8) | 4 (6.2) | 2 (3.1) | 0 | 0.08 | |
| LAD | 16 (45.7) | 11 (31.4) | 6 (17.1) | 2 (5.7) | 48 (73.8) | 15 (23.1) | 2 (3.1) | 0 | 0.005 | |
| Cx | 23 (65.7) | 11 (31.4) | 0 | 1 (2.9) | 57 (87.7) | 6 (9.2) | 2 (3.1) | 0 | 0.01 | |
| RCA | 28 (80.0) | 4 (11.4) | 3 (8.6) | 0 | 56 (86.2) | 9 (13.8) | 0 | 0 | 0.056 | |
| Aortic arch | 20 (57.1) | 10 (28.6) | 5 (14.3) | 0 | 49 (75.4) | 13 (20.0) | 3 (4.6) | 0 | 0.1 | |
| Descending aorta | 15 (42.9) | 12 (34.3) | 5 (14.3) | 3 (8.6) | 43 (58.0) | 15 (23.1) | 6 (9.2) | 1 (1.5) | 0.08 | |
Table demonstrates CAC progression after TIR in patient group and baseline progression of CAC developed in matched CT interval times in control group that did not receive TIR. Data showed in number (percentage) for patients with progression of CAC severity (P values for chi-square test). Scale for extension of CAC; None: No changes; Mild: One-degree changes (none to mild; mild to moderate, moderate to severe); Moderate: Two-degree changes (none to moderate, mild to severe); Severe: Three-degree changes (none to severe). CAC, coronary artery calcification; TIR, thoracic irradiation; Cx, left circumflex coronary artery; LAD, left anterior descending coronary artery; LM, left main coronary artery; RCA, right coronary artery.