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. 2020 Mar;12(3):349–362. doi: 10.21037/jtd.2020.01.25

Table 1. Characteristics of studies included in the meta-analysis.

First author Year Country Ethnicity Source of control Genotyping method Cases/controls Genes Polymorphisms NOS, total scores
Bayramoglu 2009 Turkey Asian HB PCR-RFLP 200/100 MMP9 –1562 C/T 6
Bayramoglu 2011 Turkey Asian HB PCR-RFLP 200/100 MMP2 –1306 C/T 6
Fakhoury 2012 Lebanon Caucasian PB PCR-RFLP 41/51 MMP1 –1607 1G/2G 8
Fang 2005 China Asian PB PCR-RFLP 243/350 MMP3 –1171 5A/6A 8
Gonzalez-Arriaga 2012 Spain Caucasian HB PCR-RFLP 716/534 MMP3, MMP9 –1171 5A/6A,
–1562 C/T
6
Gonzalez-Arriaga 2008 Spain Caucasian HB PCR-RFLP 501/510 MMP1, MMP13 –1607 1G/2G,
–77 A/G
7
Hart 2011 Norway Caucasian PB TaqMan 436/434 MMP1 –1607 1G/2G 9
Hu 2005 China Asian PB PCR-RFLP 744/747 MMP9 R279Q 8
Jia 2009 China Asian PB PCR-RFLP 370/436 MMP2 –735 C/T 8
Liu 2011 China Asian PB PCR-RFLP 825/825 MMP1 –1607 1G/2G 9
Lu 2017 China Asian PB PCR-RFLP 260/219 MMP7 –181 A/G 8
Peng 2010 China Asian PB PCR-RFLP 420/419 MMP12, MMP13 –82 A/G, –77 A/G 8
Rollin 2007 France Caucasian HB PCR-RFLP 90/90 MMP2, MMP9 –1306 C/T, –735 C/T, –1562 C/T 7
Sanli 2013 Turkey Asian PB PCR-RFLP 132/80 MMP7 –181 A/G 7
Song 2007 China Asian PB PCR-RFLP 163/148 MMP2 –1306 C/T 8
Su 2006 USA Caucasian PB TaqMan 2,014/1,323 MMP1, MMP3, MMP12 –1607 1G/2G, –1171 5A/6A, –82 A/G 7
Wang 2013 China Asian PB PCR-RFLP 300/300 MMP12 –82 A/G 8
Wang 2013 China Asian PB PCR-RFLP 300/300 MMP13 –77 A/G 8
Yu 2002 China Asian PB PCR-DHPLC 781/852 MMP2 –1306 C/T 8
Zhang 2005 China Asian PB PCR-RFLP 243/350 MMP7 –181 A/G 8
Zhang 2006 China Asian PB PCR-RFLP 150/200 MMP1 –1607 1G/2G 8
Zhao 2007 China Asian PB PCR-RFLP 50/50 MMP9 R279Q 8
Zhou 2005 China Asian PB PCR-RFLP 770/777 MMP2 –735 C/T 8
Zhang 2005 China Asian PB PCR-RFLP 150/200 MMP9 –1562 C/T 8

HB, hospital-based; PB, population-based; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; PCR-DHPLC, polymerase chain reaction-denaturing high-performance liquid chromatography.