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. 2020 Mar;12(3):349–362. doi: 10.21037/jtd.2020.01.25

Table 2. Genotype counts of the analyzed polymorphisms included in the meta-analysis.

Study Ethnicity Cases/controls Cases Controls PHWE
1G/1G 1G/2G 2G/2G 1G/1G 1G/2G 2G/2G
MMP1 -1607 1G/2G
   Su Caucasian 2,014/1,323 541 1,015 458 367 642 314 0.310
   Gonzalez-Arriaga Caucasian 501/510 128 248 125 119 259 132 0.712
   Hart Caucasian 436/434 115 207 114 132 198 104 0.081
   Liu Asian 825/825 74 323 428 100 367 358 0.691
   Fakhoury Caucasian 41/51 5 17 19 7 16 28 0.081
   Zhang Asian 150/200 32 70 48 60 98 42 0.865
MMP2 -1306 C/T CC CT TT CC CT TT
   Yu Asian 781/852 644 127 10 585 248 19 0.220
   Rollin Caucasian 90/90 60 28 2 60 29 1 0.217
   Bayramoglu Asian 200/100 123 73 4 65 32 3 0.692
   Song Asian 163/148 129 32 2 100 44 4 0.747
MMP2 -735 C/T CC CT TT CC CT TT
   Zhou Asian 770/777 506 230 34 425 313 39 0.052
   Rollin Caucasian 89/90 69 18 2 67 21 2 0.816
   Jia Asian 370/436 260 96 14 292 123 21 0.092
MMP3 -1171 5A/6A 5A/5A 5A/6A 6A/6A 5A/5A 5A/6A 6A/6A
   Fang Asian 243/350 7 73 163 8 105 237 0.358
   Su Caucasian 2,014/1,323 485 1,012 517 325 648 350 0.466
   Gonzalez-Arriaga Caucasian 716/534 164 367 185 119 276 139 0.417
MMP7 -181 A/G A/A A/G G/G A/A A/G G/G
   Zhang Asian 243/350 200 40 3 316 33 1 0.888
   Sanli Asian 132/80 120 10 2 79 1 0 0.955
   Lu Asian 260/219 182 78 0 176 43 0 0.107
MMP9 -1562 C/T CC CT TT CC CT TT
   Zhang Asian 150/200 83 60 7 155 42 3 0.936
   Rollin Caucasian 90/90 68 22 0 64 21 5 0.085
   Bayramoglu Asian 200/100 150 48 2 67 30 3 0.871
   Gonzalez-Arriaga Caucasian 762/649 581 174 7 483 148 18 0.110
MMP9 R279Q RR RQ QQ RR RQ QQ
   Hu Asian 744/747 357 323 64 343 323 81 0.704
   Zhao Asian 50/50 24 20 6 14 28 8 0.335
MMP12 -82A/G A/A A/G G/G A/A A/G G/G
   Su Caucasian 2,014/1,323 1,535 449 30 1,008 289 26 0.324
   Wang Asian 300/300 290 10 0 287 13 0 0.701
   Peng Asian 420/419 404 16 0 399 20 0 0.617
MMP13 -77A/G A/A A/G G/G A/A A/G G/G
   Gonzalez-Arriaga Caucasian 501/506 248 208 45 267 197 42 0.508
   Wang Asian 300/300 85 132 83 55 156 89 0.354
   Peng Asian 420/419 105 207 108 91 227 101 0.085

PHWE, P value of Hardy-Weinberg Equilibrium.