Table 3. Effects of different CPAP levels on breathing pattern in COPD patients.
CPAP (cmH2O) | RR (b/min) | Ti (s) | Ti/Ttot | Vt (L) | Ve (L/min) | Vt/Ti (L/s) |
---|---|---|---|---|---|---|
SB | 17.43±1.11 | 3.74±0.26 | 1.50±0.10 | 0.41±0.01 | 0.72±0.05 | 11.86±0.88 |
4 | 21.15±1.53* | 3.12±0.22* | 1.37±0.11 | 0.44±0.02* | 0.92±0.06* | 18.81±1.36* |
5 | 22.93±1.93*# | 3.03±0.27* | 1.43±0.13 | 0.48±0.02* | 1.05±0.07*# | 22.68±1.66*# |
6 | 23.24±1.78*# | 2.90±0.26*# | 1.31±0.13* | 0.46±0.02* | 1.02±0.08*# | 22.63±1.94*# |
7 | 22.55±1.51* | 2.81±0.19* | 1.28±0.09* | 0.46±0.02* | 0.96±0.08* | 20.87±1.78* |
8 | 24.31±1.75*#§ | 2.77±0.23*# | 1.29±0.10*† | 0.47±0.02* | 1.01±0.08* | 23.75±2.26*#§ |
9 | 24.06±1.69*#§ | 2.77±0.19*# | 1.24±0.09*† | 0.45±0.02* | 0.90±0.08*†‡ | 21.40±2.22* |
10 | 25.73±1.98*#‡§ | 2.66±0.21*#† | 1.22±0.09*#† | 0.46±0.02* | 0.85±0.07†‡ | 21.57±2.36* |
F value | 10.438 | 3.817 | 2.583 | 6.101 | 11.808 | 10.481 |
P value | <0.001 | 0.008 | 0.041 | <0.001 | <0.001 | <0.001 |
Data are presented as mean ± SE unless otherwise stated; P results of repeated analysis of variance (ANVOA) comparison between different CPAP levels; *P<0.05 vs. steady breathing; #P<0.05 vs. 4 cmH2O level; †P<0.05 vs. 5 cmH2O level; ‡P<0.05 vs. 6 cmH2O; §P<0.05 vs. 7 cmH2O level; ÄP<0.05 vs. 8 cmH2O level; ▲P<0.05 vs. 9 cmH2O level. CPAP, continue positive airway pressure; RR, respiratory rate; Ttot, respiratory cycle time; Ti, inspiratory time; Ti/Ttot, inspiratory duty ratio; Vt, tidal volume; Ve, minute ventilation; Vt/Ti, inspiratory flow; SB, stable breathing.