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. 2020 Mar;12(3):448–456. doi: 10.21037/jtd.2020.01.14

Table 3. Univariate and multivariate Cox hazards regression analyses of the clinicopathological parameters in all thymic epithelial tumor patients.

Variable Univariate Multivariate
HR 95% CI P value HR 95% CI P value
Age (<65 vs. ≥65) 8.784 2.339–32.994 0.001 4.617 1.128–18.9 0.033
Sex (male vs. female) 1.16 0.671–2.007 0.595
Tumor size (<40 vs. ≥40 mm) 0.567 0.153–2.106 0.396
Masaoka stage (I, II vs. III, IV) 6.825 2.071–22.49 0.002 2.262 0.505–10.14 0.286
WHO histological grade (thymic cancer vs. thymoma) 7.177 2.129–24.197 0.001 2.149 0.48–9.62 0.317
BMP-7 staining (positive vs. negative) 5.181 1.397–19.211 0.014 2.115 0.503–8.89 0.307

HR, hazard ratio; CI, confidence interval; BMP-7, bone morphogenetic protein-7.