Table 3. Univariate and multivariate Cox hazards regression analyses of the clinicopathological parameters in all thymic epithelial tumor patients.
Variable | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | ||
Age (<65 vs. ≥65) | 8.784 | 2.339–32.994 | 0.001 | 4.617 | 1.128–18.9 | 0.033 | |
Sex (male vs. female) | 1.16 | 0.671–2.007 | 0.595 | ||||
Tumor size (<40 vs. ≥40 mm) | 0.567 | 0.153–2.106 | 0.396 | ||||
Masaoka stage (I, II vs. III, IV) | 6.825 | 2.071–22.49 | 0.002 | 2.262 | 0.505–10.14 | 0.286 | |
WHO histological grade (thymic cancer vs. thymoma) | 7.177 | 2.129–24.197 | 0.001 | 2.149 | 0.48–9.62 | 0.317 | |
BMP-7 staining (positive vs. negative) | 5.181 | 1.397–19.211 | 0.014 | 2.115 | 0.503–8.89 | 0.307 |
HR, hazard ratio; CI, confidence interval; BMP-7, bone morphogenetic protein-7.