Figure 5.
The effect of miR-429/Cxcl1 axis on biological behavior of OGD/R-treated BMECs. A and B, Overexpression of miR-429 can significantly reduce the apoptotic rate of cells compared with the control group, whereas overexpression of Cxcl1 can significantly reverse this effect, **P < .01 versus control, ## P < .01 versus the miR-429 mimic group. C and D, The expression of proapoptosis protein Bax and antiapoptosis protein BCL-2 in different conditions, **P < .01, ## P < .01. E, Overexpression of miR-429 can significantly induce the viability of cells compared with the control group, whereas overexpression of Cxcl1 can significantly reverse this effect, **P < .01, ## P < .01. BMECs indicates microvascular endothelial cells; OGD/R, oxygen glucose deprivation/reoxygenation.