REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
chicken polyclonal anti-GFP	Aves Labs	Cat# GFP-1020; RRID: AB_10000240
rabbit polyclonal anti-RFP	Rockland	#600401379; RRID: AB_2209751
mouse monoclonal anti-GFAP, clone GA5	Millipore	MAB360; RRID: AB_11212597
rabbit polyclonal anti-GFAP	Millipore	Cat# AB5804; RRID: AB_2109645
rat monoclonal anti-CD45	BD	#550539; RRID: AB_2174426
rat monoclonal anti-CD31	BD	#550274; RRID: AB_393571
rabbit monoclonal anti-ERG	Abcam	Cat# ab92513; RRID: AB_2630401
rabbit monoclonal anti-S100ß	Abcam	Cat# ab52642; RRID: AB_882426
rabbit polyclonal anti-SOX2	Abcam	Cat# ab97959; RRID: AB_2341193
Donkey anti-chicken IgY (H+L), Alexa Fluor 488	Jackson ImmunoResearch	Cat# 703-545-155; RRID: AB_2340375
Goat anti-Rat IgG (H+L), Alexa Fluor 546	Thermo Fisher Scientific	Cat# A-11081; RRID: AB_2534125
Donkey anti-Rabbit IgG (H+L), Alexa Fluor 546	Thermo Fisher Scientific	Cat# A10040; RRID: AB_2534016
Donkey anti-Rat IgG (H+L), Alexa Fluor 647	Jackson ImmunoResearch Labs	Cat# 712-605-150; RRID: AB_2340693
Donkey anti-Mouse (H+L), Alexa Fluor 647	Jackson ImmunoResearch Labs	Cat# 715-605-150; RRID: AB_2340862
4',6-Diamidino-2-Phenylindole, Dihydrochloride (DAPI)	Thermo Fisher Scientific	Cat# D1306; RRID: AB_2629482
CMC-Protein-A-gold	Cell Microscopy Core (Utrecht)	N/A
Click-iT EdU Imaging Kit	Thermo Fisher Scientific	Cat# C10338
Bacterial and Virus Strains
RABV SAD ΔG ER-GFP (EnvA)	This paper	N/A
RABV SAD ΔG mito tag-RFP (EnvA)	This paper	N/A
RABV SAD ΔG mito-GFP (EnvA)	Motori et al., 2013	N/A
RABV SAD ΔG mito-PA-GFP (EnvA)	This paper	N/A
AAV5-GFAP(0.7)-mCherry-peroxisome-2A-eBFP2-WPRE	This paper	N/A
AAV5-GFAP(0.7)-emerald-lamp1-2A-mCherry-WPRE	This paper	N/A
AAV5-GFAP(0.7)-mito-GCamp6f-P2A-mCherry-WPRE	This paper	N/A
AAV5-gfaABC1D-cyto-GCamp6f	Haustein et al., 2014	N/A
AAV5-GFAP(0.7)-AKAP1-mRFP-2A-mitoGCamp6f-WPRE	This paper	N/A
AAV5-GFAP(0.7)-AKAP1-mRFP-ER-2A-mitoGCamp6f-WPRE	This paper	N/A
Chemicals, Peptides, and Recombinant Proteins
Tamoxifen	Sigma-Aldrich	Cat# T5648, CAS: 10540-29-1
Corn-oil	Sigma-Aldrich	Cat# C8267, CAS: 8001-30-7
Dextran, Texas Red, 70.000MW	Thermo Fisher Scientific	Cat# D1864
Paraformaldehyde	Sigma-Aldrich	Cat# P6148, CAS: 30525-89-4
Glutaraldehyde 25%	Merck	Cat# 354400, CAS: 113-30-8
Deposited Data
Mass spectrometry dataset	Mendeley Data	https://doi.org/10.17632/ps8677yrjm.1
Experimental Models: Organisms/Strains
Mouse: hGFAP-TVA	Holland and Varmus, 1998	N/A
Mouse: Mfn1loxP	Lee et al., 2012	N/A
Mouse: Mfn2loxP	Lee et al., 2012	N/A
Mouse: Yme1lloxP	Anand et al., 2014	N/A
Mouse: hGFAP-CreER	Chow et al., 2008	N/A
Mouse: Glast-CreERT2	Mori et al., 2006	N/A
Mouse: Gt(ROSA26)SorStop-mito-YFP	Sterky et al., 2011	N/A
Mouse: Gt(ROSA26)SorStop-GCaMP3	Zariwala et al., 2012	N/A
Mouse: Gt(ROSA26)SorStop-tdTomato	Madisen et al., 2010	N/A
Recombinant DNA
Plasmid: mito-PAGFP	Addgene	#23348
Plasmid: ER-GFP	Snapp et al., 2006	N/A
Plasmid: mCherry-Peroxisomes-2	Addgene	#54520
Plasmid: Emerald-Lysosomes-20	Addgene	#56476
Plasmid: mito-GCamp6f-2A-mCherry	This paper	N/A
Plasmid: gfaABC1D-cyto-GCaMP6f	Addgene	#52925
Plasmid: AKAP1-mRFP	Csordas et al., 2006	N/A
Plasmid: AKAP1-mRFP-ER(ubc)	Csordás et al., 2006	N/A
Software and Algorithms
ImageJ	NIH	https://imagej.nih.gov/ij/; RRID: SCR_003070
Fiji	Max-Planck-Gesellschaft	http://fiji.sc; RRID: SCR_002285
TurboReg	http://bigwww.epfl.ch/thevenaz/turboreg/	RRID: SCR_014308
moco plugin	https://github.com/NTCColumbia/moco	N/A
FindFoci	http://www.sussex.ac.uk/gdsc/intranet/microscopy/UserSupport/AnalysisProtocol/imagej/findfoci	N/A
FACS Aria Fusion cell sorter	BD Biosciences	N/A
FACS Diva software	BD Biosciences, version 8.0.1	N/A
Igenuity Pathway Analysis (IPA)	Qiagen	http://www.ingenuity.com/products/pathways_analysis.html; RRID: SCR_008653
GraphPad Prism 7.0	GraphPad Software	https://www.graphpad.com/scientific-software/prism; RRID: SCR_002798
Origin 2018	Origin Lab	RRID: SCR_014212
Huygens Professional	Scientific Volume Imaging	RRID: SCR_014237
Adobe Illustrator CS6	Adobe	RRID: SCR_014198
Photoshop CC 2017	Adobe	https://www.adobe.com/
Imaris	Bitplane	https://imaris.oxinst.com/; RRID: SCR_007370
Igor Pro v7.0.4.1	WaveMetrics	http://www.wavemetrics.com/products/igorpro/igorpro.htm; RRID: SCR_000325
AstroSparks	This Paper	N/A