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. 2020 Mar 16;9(3):241. doi: 10.3390/antiox9030241

Table 2.

Adverse effects and benefits of dietary nitrites/nitrates.

Adverse Effect Reference Benefits Reference
Gastric cancer Kim et al. [47]
Ward et al. [48]
Keszei et al. [49]
Xie et al. [83]
Song et al. [57]
Zheng et al. [62]
Adult glioma Dubrow et al. [53];
Xie et al. [83]
Colorectal cancer De Roos et al. [54];
Cross et al. [55];
DellaValle [51];
Cantwell et al. [84]
Xie et al. [83];
Van Hecke et al. [60]
Bestide et al. [61]
Reduction of blood pressure Kapil et al. [65];
Berry et al. [66]; Ashworth et al. [67]; Amaral et al. [69];
Ling et al. [70];
Sievro et al. [71]
Esophageal cancer Cross et al. [55];
Keszei et al. [49];
Xie et al. [83]
Atherosclerosis prevention Bondonno et al. [78]; Burnley-Hall et al. [79]
Thyroid cancer Ward et al. [48]; Aschebrook-Kilfoy et al. [59]; Xie et al. [83];
Bahadoran et al. [56]
Protection against ischemia-
reperfusion
Yang et al. [46];
Lefer et al. [80]
Renal cell carcinoma Weyer et al. [50];
DellaVale et al. [51];
Grieb [52];
Xie et al. [83];
Hu et al. [58]
Exercise capacity Coggan et al. [81] Coggan et al. [82]
Methemoglobinemia Chan et al. [63] Stroke prevention Bondonno et al. [78];
Burnley-Hall et al. [79]
Hypothyroidism Ward et al. [48];
Xie et al. [83]
Insulin resistance, glucose tolerance Ghasemi, Ghebi [72]; Khalifi et al. [73];
Gilchrist et al. [74]; Cermak et al. [75]
Breast cancer Yang et al. [46];
Xie et al. [83]
Reduction of triglycerides Zand et al. [76]
Nitrosative stress D’Ischia et al. [37]