Skip to main content
. 2020 Mar 13;21(6):1976. doi: 10.3390/ijms21061976
AMD Age-related macular degeneration
RPE Retinal pigment epithelial cells
dKO Double knockout
WT Wild type
NFE2L2 Nuclear Factor, Erythroid 2 Like 2
PGC1α Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
LC3B Microtubule-associated proteins 1A/1B light chain 3B
PINK1 PTEN-induced kinase 1
PARKIN E3 ubiquitin ligase
LAMP2 Lysosome-associated membrane protein 2
Rab(5/7) RAS-related GTP-binding proteins (5/7)
PRCs Photoreceptor cells
POS Photoreceptor outer segments
p62/SQSTM1 Sequestosome-1/ ubiquitin-binding protein p62
OMM Outer mitochondrial membrane
NBR1 Neighbor of BRCA1 gene 1 protein
OPTN Optineurin
AMBRA1 Autophagy and beclin-1 regulator 1
LIR LC3-interacting region
Bnip3 BCL2 interacting protein 3
Nix/Bnip3L BCL2-like 3
FUNDC1 FUN14 domain-containing 1
Bcl2L13 BCL2-like 13
TOM20 Mitochondrial import receptor subunit TOM20
TEM Transmission electron microscopy
TMN Total mitochondrial number
pS65 Phospho-ubiquitin serine 65
ATP Adenosine triphosphate
AF Autofluorescence
ROS Reactive oxygen species
RNS Reactive nitrogen species
AMPK 5′-adenosine monophosphate-activated protein kinase
NaIO3 Sodium iodate
NAC N-acetylcysteine