Figure 1.
Selected mice models of altered phosphate metabolism and their mechanisms. Green arrows: activation, red arrows: down regulation, blue arrows: pathway. References: [117,127,128,130,132,133]. Cyp24a1: 24-hydroxyvitamin D-1α-hydroxylase; Cyp27b1: 25-hydroxyvitamin D-1α-hydroxylase; FGF23: fibroblast growth factor 23; Galnt3: N-acetylgalactosaminyltransferase 3; NPT2a: renal sodium-dependent phosphate co-transporter type IIa; NPT2c: renal sodium-dependent phosphate co-transporter type IIc.