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The maximum tolerated dose (MTD) of TLD1433 in wild type zebrafish embryos and in the ectopic and orthotopic CM tumour model.
| TLD1433 Administration Type | Maximum Tolerated Dose (MTD) | |
|---|---|---|
| Wild Type Embryos | CM Engrafted Embryos Ectopic and Orthotopic Model |
|
| Water | 9.2 nM | 4.6 nM |
| Intravenous | 4.6 mM | 2.3 mM |
| Retro-orbital | 4.6 mM | 2.3 mM |
