Table 3.
PERG amplitudes-Group II
| Group II (mice groups) |
Time points | Amplitude(μV; mean ± SEM) | KS normality test (p value) |
Two-way ANOVA (p value) |
Tukey’s multiple comparison test p value and 95% confidence interval (CI) |
||
|---|---|---|---|---|---|---|---|
| Control/Veh-ttd (vs) EAE/Veh-ttd | Control/Veh-ttd (vs) EAE-Klf4fl/fl/Cre-ttd | EAE/Veh-ttd (vs) EAE Klf4fl/fl/ Cre-ttd | |||||
| Control | Baseline | 26.93 ± 1.99 | >0.1 | Row factor: p = 0.0100; column factor: p = 0.0003; interaction: row factor x column factor: p = 0.028 |
p = 0.808 CI: –5.102 to 8.54 |
p = 0.99 CI: –6.624 to 7.022 |
p = 0.846 CI: –8.344 to 5.301 |
| EAE | Baseline | 25.21 ± 1.60 | >0.1 | ||||
| EAE-Klf4fl/fl | Baseline | 26.74 ± 1.31 | >0.1 | ||||
| Control | 9 MPS | 27.60 ± 1.92 | >0.1 |
p = 0.001
CI: 4.037 to 17.68 |
p = 0.001
CI: 4.264 to 17.91 |
p = 0.99 CI: –6.596 to 7.049 |
|
| EAE | 9 MPS | 16.74 ± 1.70 | >0.1 | ||||
| EAE-Klf4fl/fl | 9 MPS | 16.52 ± 1.19 | >0.1 | ||||
| Control-Veh-ttd | 18 MPS (9 MPI) |
28.11 ± 3.87 | >0.1 |
p = 0.0002
CI: 5.819 to 19.46 |
p = 0.092 CI: –0.8202 to 12.82 |
p = 0.057 CI: –13.46 to 0.1831 |
|
| EAE-Veh-ttd | 18 MPS (9 MPI) |
15.46 ± 1.52 | >0.1 | ||||
| EAE-Klf4fl/fl - Cre-ttd | 18 MPS (9 MPI) |
22.10 ± 1.36 | >0.1 | ||||
Bold indicates statistically significant difference of p values.